SNIPE, a newly characterized biological defense system, directly protects bacteria by chopping up invading viral DNA.

Researchers uncovered how cells selectively destroy certain microRNAs — key gene regulators — through a mechanism that requires two RNA signals working together.

Study finds a common bacterium can suppress the body’s early warning system in wounds, causing infections to persist and create an environment that allows other bacteria to take hold.

Computational biologist Sergei Kotelnikov is working to develop new methods in protein modeling as part of the School of Science Dean’s Postdoctoral Fellowship.

“We cannot be effective scientists if we are unhappy or unhealthy outside of the lab,” says “Committed to Caring” honoree Sara Prescott.

An AI model generates novel proteins based on how they vibrate and move, opening new possibilities for dynamic biomaterials and adaptive therapeutics.

The Institute also ranks second in seven subject areas.

As an aspiring physician-scientist and editor-in-chief of The Tech, MIT senior Alex Tang has found inspiration in the lives of patients and others in his community.

The method allows researchers to observe biomolecular complexes in a quick, accurate, and budget-friendly way, providing new insights into bacterial protein synthesis.

Impairments of this circuit may help to explain why some people with schizophrenia lose touch with reality.

MIT researchers uncovered the roles of bacterial species from the environment as they consume biodegradable plastic.

The technology could enable fast, point-of-care diagnoses for pneumonia and other lung conditions.

Assistant Professor Matthew Jones is working to decode molecular processes on the genetic, epigenetic, and microenvironment levels to anticipate how and when tumors evolve to resist treatment.

Eliezer Calo’s studies of craniofacial malformations have yielded insight into protein synthesis and embryonic development.

Research reveals how cells may activate a compensation system that can reduce the effects of harmful genetic mutations. This could inform gene therapy development.

Assistant Professor Alison Ringel will investigate the intersection of immunology and aging biology, aiming to define mechanisms that underlie aging-related decline, thanks to a grant from the foundation.

Offering substantial prize funding alongside workshops, classes, and mentorship, the initiative helps translate early-stage biotech research into venture-ready innovation.

By providing holistic information on a cell, an AI-driven method could help scientists better understand disease mechanisms and plan experiments.

Zuri Sullivan, a new assistant professor of biology and Whitehead Institute member, studies why we get sick, and whether aspects of illness, such as disrupted appetite, contribute to host defense.

MIT researchers used a large language model to optimize the genetic sequences of proteins manufactured by yeast, making production more efficient.

The MIT senior will pursue a master’s degree at Cambridge University in the U.K. this fall.

Somatostatin-expressing neurons follow a unique trajectory when forming connections in the visual cortex that may help establish the conditions needed for sensory experience to refine circuits.

Founded by three MIT alumni, Gensaic uses AI-guided protein design to deliver RNA and other therapeutic molecules to specific cells or areas of the body.

Researchers uncover a hidden mechanism that allows cancer to develop aggressive mutations.

Professor, mentor, and leader at MIT for more than 50 years shaped fundamental understandings of cell adhesion, the extracellular matrix, and molecular mechanisms of metastasis.

The program recognizes outstanding mentorship of graduate students.

Time and again, an unassuming roundworm has illuminated aspects of biology with major consequences for human health.

New research suggests liver cells exposed to too much fat revert to an immature state that is more susceptible to cancer-causing mutations.

Assistant Professor Yunha Hwang utilizes microbial genomes to examine the language of biology. Her appointment reflects MIT’s commitment to exploring the intersection of genetics research and AI.

Tracking how fruit fly motor neurons edit their RNA, neurobiologists cataloged hundreds of target sites and varying editing rates, finding many edits altered communication- and function-related proteins.

The approach could apply to more complex tissues and organs, helping researchers to identify early signs of disease.

Angela Koehler, Iain Cheeseman, and Katharina Ribbeck are shaping the collaborative as a platform for transformative research, translation, and talent development across MIT.

With its circular single-stranded DNA molecules, MIT spinout Kano Therapeutics plans to make gene and cell therapies safer and more effective.

Eleven new professors join the departments of Biology; Brain and Cognitive Sciences; Earth, Atmospheric and Planetary Sciences; Mathematics; and Physics.

New findings may help researchers identify genetic mutations that contribute to rare diseases, by studying when and how single genes produce multiple versions of proteins.

The new design from MIT engineers could pump up many biohybrid builds.

Seven speakers from around the country convened at MIT to describe some of the latest research on the neural mechanisms that we need to survive.

Alnylam Pharmaceuticals establishes named fund in honor of its co-founder, an MIT Institute Professor and Nobel laureate.

The KATMAP model, developed by researchers in the Department of Biology, can predict alternative cell splicing, which allows cells to create endless diversity from the same sets of genetic blueprints.

Mary Gallagher’s deeply rooted MIT experience and love of all life supports growth at the MIT Department of Biology.

Professors Facundo Batista and Dina Katabi, along with three additional MIT alumni, are honored for their outstanding professional achievement and commitment to service.

Scientists identified how circuit connections in fruit flies tune to the right size and degree of signal transmission capability. Understanding this could lead to a way to tweak abnormal signal transmission in certain disorders.

Twelve START.nano companies competed for the grand prize of nanoBucks to be used at MIT.nano’s facilities.

Enabled by a new high-resolution mapping technique, the findings overturn a long-held belief that the genome loses its 3D structure when cells divide.

The promoter editing system could be used to fine-tune gene therapy or to more efficiently reprogram cells for therapeutic use.